Overview
Horizon Discovery provides cell engineering tools and services using gene editing technologies like CRISPR, base editing, and RNAi for basic research, drug discovery, and therapeutic development. Their offerings include research reagents, screening and cell line engineering services, BioProduction cell lines for biologics manufacturing, and reference standards for diagnostics. These solutions support gene function studies, target identification, pathway exploration, and precision medicine applications.
Frequently asked questions
- What gene editing technologies does Horizon Discovery offer?
- Horizon offers CRISPR-Cas9, base editing, and RNAi technologies, including predesigned genome-wide knockout reagents, lentiviral guide RNAs, and tools for HDR knock-in and site-specific editing.
- What services are available for drug discovery and cell line engineering?
- Services include functional genomic screening with CRISPR and RNAi, single cell RNAseq-linked CRISPR screening, custom cell line engineering, and engineered models for target validation and patient population studies.
- What applications do Horizon's cell lines support?
- Horizon's cell lines enable study of functional mutations at endogenous levels, target identification and validation, identification of responsive or resistant patient populations, biologics manufacturing with CHO lines, and disease mechanism research.