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Codexis

Codexis: Enzyme Engineering & RNA Manufacturing

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Overview

Codexis specializes in enzyme engineering and biocatalysis solutions for pharmaceutical manufacturing, including custom enzymes for small molecule APIs via CodeEvolver® technology. Their ECO Synthesis™ platform enables scalable, sustainable production of RNAi therapeutics like siRNA through enzymatic synthesis, reducing waste and improving efficiency over chemical methods. With over 22 years of expertise, they support greener manufacturing for next-generation oligonucleotide therapies.

Frequently asked questions

What are Codexis' key capabilities in pharma manufacturing?
Codexis offers enzyme engineering with CodeEvolver® AI-driven technology for custom enzymes in small molecule APIs and ECO Synthesis™ for scalable RNAi/siRNA production, improving yield, quality, and sustainability.
How does ECO Synthesis™ address RNA manufacturing challenges?
ECO Synthesis™ uses engineered enzymes for high-fidelity RNA synthesis and ligation, enabling gram-scale production with minimal waste, higher efficiency, and scalability for therapeutics.
What industries or geographies does Codexis serve?
Codexis provides biocatalysis and RNA manufacturing solutions to pharmaceutical companies globally, focusing on RNAi therapeutics, small molecule APIs, and sustainable bioprocessing.