Intelligence · Clinical Pipeline
R&D Pipeline Programs
ClinicalTrials.gov programs linked to pharma sponsors — phase, modality, and trial IDs for BD and competitive intelligence.
- Programs indexed
- 20,548
- Companies
- 1,769
- Drugs tracked
- 4,797
Quick answer
NovaPharmaNews tracks 20,548 pharmaceutical R&D pipeline programs sourced from ClinicalTrials.gov, linked to sponsor companies. Each profile includes development phase, modality, trial status, NCT identifiers, and indication text — searchable for business development and competitive intelligence.
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Cryo-Touch II
Pacira Ireland Limited
Facial Wrinkles
2 trials -
Cryo-Touch III
Pacira Ireland Limited
Facial Wrinkles
1 trial -
DARAXONRASIB (RMC-6236), GEMCITABINE HYDROCHLORIDE, PACLITAXEL ALBUMIN-BOUND, GEMCITABINE HYDROCHLORIDE, OXALIPLATIN, GEMCITABINE HYDROCHLORIDE, DARAXONRASIB (RMC-6236), GEMCITABINE HYDROCHLORIDE, GEMCITABINE HYDROCHLORIDE, IRINOTECAN, IRINOTECAN HYDROCHLORIDE, FOLINIC ACID, FLUOROURACIL, GEMCITABINE HYDROCHLORIDE
Revolution Medicines
Metastatic Pancreatic Ductal Adenocarcinoma
1 trial -
DEXAMETHASONE, CAPECITABINE , OXALIPLATIN , FLUOROURACIL , FOLINIC ACID, METOCLOPRAMIDE, ONDANSETRON
The George Institute
locally advanced rectal cancer
1 trial -
DEXMEDETOMIDINE , 18F-DPA-714
Pari Pharma GmbH
Patients who survive a COVID ARDS in intensive care must be weaned off invasive mechanical ventilation as quickly as possible. 60% of these patients present with intensive care delirium, a serious event that causes excess mortality and potential acute and late complications, since 30% of patients who present with delirium develop cognitive sequelae. Severe neuroinflammation is considered to be one of the main pathophysiological mechanisms causing delirium during ventilatory weaning. In addition to its sedative properties, dexmedetomidine has neuroprotective effects. In certain experimental models, it reduces cerebral inflammation by acting directly on the microglial phenotype. The role of this chronic neuroinflammatory state on cognitive capacity and reserve is beginning to emerge in the literature, regardless of the initial stress (surgery, head injury or Alzheimer's-type dementia), and is therefore capable of influencing patients' quality of life. The assessment of this neuroinflammation using non-invasive tools would appear to be of prime importance in the management of post-COVID neuro injured patients, as well as the evaluation of potential neuroprotective agents such as dexmedetomidine.
1 trial -
DIAMICRON 60MG, comprimé sécable à libération modifiée, Placebo S05762, METFORMIN, Forxiga 10 mg film-coated tablets
The George Institute
Type 2 Diabetes inadequately controlled with dapagliflozin with or without metformin
1 trial -
DOXYCYCLINE SANDOZ 100 mg, comprimé sécable, EXTENCILLINE 2,4 MUI, poudre et solvant pour suspension injectable IM
Pari Pharma GmbH
early syphilis
1 trial -
DUOFAG, Chlorid sodný B. Braun 0,9 % infuzní roztok
Lacuna Pharma Pty Ltd
Complicated skin wounds (wounds healing per secundam via granulation tissue) - either as a complication of healing of acute wounds (infected surgical or traumatic wounds) or chronic wounds, in both cases infected with S. aureus and/or P. aeruginosa.
1 trial -
Dapagliflozin+Standard Treatment for 12 weeks,washout period for 4 weeks,then Standard Treatment alone for12 weeks
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Pediatric Hereditary Kidney Diseases
1 trial -
Darleukin, Fibromun
Philogen S.p.A.
Malignant melanoma of the skin in patients with locally advanced and fully resectable melanoma with/without prior therapy and presence of injectable cutaneous and/or subcutaneous or nodal lesions
1 trial -
Datopotamab deruxtecan, DOCETAXEL
AstraZeneca AB
TROP2 NMR-positive advanced or metastatic non-squamous non-small cell lung cancer without actionable genomic alterations.
1 trial -
Datopotamab deruxtecan, Rilvegostomig, MYCOPHENOLATE MOFETIL, INFLIXIMAB, KEYTRUDA 25 mg/mL concentrate for solution for infusion
AstraZeneca AB
Locally-advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) with high PD-L1 expression (TC ≥ 50%) and without actionable genomic alterations.
1 trial -
Daunoblastin 20 mg Pulver zur Herstellung einer Infusions- oder Injektionslösung, Matching placebo tablets without active substance, Idarubicin Ebewe 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung, Quizartinib, Citarabina Hikma 100mg/5mL Soluzione Iniettabile, Quizartinib
Daiichi Sankyo
Acute myeloid leukemia
1 trial -
Dazodalibep, The placebo is formulated as sterile liquid intended for intravenous infusion following dilution in normal saline. The nominal volume in each vial is 5.0 mL. The placebo is aseptically filled into 6R glass vials, stoppered with a Flurotec-coated elastomeric stopper, and sealed with an aluminum overseal.
Elan Pharma International
Sjögren’s Syndrome With Moderate-toSevere Symptom State
1 trial -
Dazodalibep, The placebo is formulated as sterile liquid intended for intravenous infusion following dilution in normal saline. The placebo is aseptically filled into 6R glass vials( the nominal volume in each vial is 5.0 mL) and 20R glass vials (the nominal volume in each vial is 15.0 mL) , stoppered with a Flurotec-coated elastomeric stopper, and sealed with an aluminum overseal.
Elan Pharma International
Sjögren’s Syndrome With Moderate-to-severe Systemic Disease Activity
1 trial -
Depigoid Grass-Mix (1000 DPP/ml), Conjunctival Provocation Test Grass-Mix LETI 30 HEP/ml, The placebo to be used in the clinical trial is the solvent used in the investigational medicinal products’ (IMPs) formulation. The resulting product is a suspension., Depigoid FORTE Grass-Mix (3000 DPP/ml)
Lacuna Pharma Pty Ltd
Allergic rhinoconjunctivitis with or without controlled asthma
1 trial -
Dexamethason CF 20 mg/ml, injectievloeistof, Imnovid 4 mg hard capsules, ELOTUZUMAB, VELCADE 3.5 mg powder for solution for injection, IXAZOMIB , Dexamethason 4 mg JENAPHARM®, Kyprolis 30 mg powder for solution for infusion, Imnovid 1 mg hard capsules, Imnovid 2 mg hard capsules, Imnovid 3 mg hard capsules, Revlimid 15 mg hard capsules, IXAZOMIB, idecabtagene vicleucel, DARZALEX 20 mg/mL concentrate for solution for infusion, Revlimid 10 mg hard capsules, IXAZOMIB, Revlimid 5 mg hard capsules, Revlimid 25 m
Celgene Europe Limited
Multiple myeloma (MM) with at least 2 prior therapies including an immunomodulatory (IMiD) compound and a proteasome inhibitor (PI) and demonstrated disease progression on or within 60 days of completion of the last therapy.
1 trial -
Dexamethasone
United Therapeutics Europe Ltd
Shoulder Pain
1 trial -
Dexmedetomidine 100 micrograms/ml concentrate for solution for infusion, Midazolam Lek 1 mg/ml raztopina za injiciranje/infundiranje
Tour Hekla
Impact on delirium of the use of DEXmedetomidine as first-line sedation in PEDIAtric intensive care:
1 trial -
Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Whooping Cough
1 trial -
Docetaxel, cisplatin and fluorouracil
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Nasopharyngeal Carcinoma
1 trial -
Donanemab, Florbetapir F18, Flortaucipir F18, Flortaucipir, FLORBETAPIR, SODIUM CHLORIDE PH. EUR.
Eli Lilly Co.
Alzheimer Disease Dementia Brain Diseases Central Nervous System Diseases Nervous System Diseases Tauopathies Neurodegenerative Diseases Neurocognitive Disorders Mental Disorders
1 trial -
Double encapsulated oral transplant of fecal microbiota, Enema transplant of fecal microbiota, Placebo double encapsulated oral transplant of fecal microbiota, Placebo coloscopic transplant of Fecal microbiota
Pari Pharma GmbH
Primary Sclerosing Cholangitis
1 trial -
Double encapsulated oral transplant of fecal microbiota, Placebo double encapsulated oral transplant of fecal microbiota
Pari Pharma GmbH
Severe Irritable Bowel Syndrome (IBS)
1 trial
Frequently asked questions
What is the NovaPharmaNews pipeline directory?
It is a searchable index of 20,548 clinical development programs grouped by sponsor company, with phase (Phase 1–3), modality, trial status, and linked NCT IDs from ClinicalTrials.gov.
Where does pipeline data come from?
Program records are derived from ClinicalTrials.gov and linked to NovaPharmaNews company profiles. Trial status and phase reflect registry data at last sync — verify on ClinicalTrials.gov before investment or partnering decisions. See our data sources page for attribution.
How do I find pipeline programs by company or phase?
Use the search box to match program name, indication, company name, or slug. Results are ordered with late-stage (Phase 3) programs first. Open any row to view the full program profile under its sponsor company.
Data attribution and licensing: Data sources