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Intelligence · Clinical Pipeline

R&D Pipeline Programs

ClinicalTrials.gov programs linked to pharma sponsors — phase, modality, and trial IDs for BD and competitive intelligence.

Programs indexed
18,156
Companies
1,062
Drugs tracked
3,385

Quick answer

NovaPharmaNews tracks 18,156 pharmaceutical R&D pipeline programs sourced from ClinicalTrials.gov, linked to sponsor companies. Each profile includes development phase, modality, trial status, NCT identifiers, and indication text — searchable for business development and competitive intelligence.

128 results for “IONIS PHARMACEUTICALS INC” Clear

  1. APOC-III-L-Rx

    IONIS PHARMACEUTICALS INC

    Elevated Triglycerides (TG)

    phase 1 small molecule completed

    1 trial

  2. AZD9150

    IONIS PHARMACEUTICALS INC

    Advanced Adult Hepatocellular Carcinoma

    phase 1 small molecule completed

    1 trial

  3. BIIB094

    IONIS PHARMACEUTICALS INC

    Parkinson's Disease

    phase 1 small molecule completed

    1 trial

  4. Eplontersen

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  5. Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer’s Disease (AD)

    IONIS PHARMACEUTICALS INC

    Alzheimer’s Disease in Individuals with Down Syndrome

    phase 1 other active

    1 trial

  6. ION251

    IONIS PHARMACEUTICALS INC

    Relapsed Multiple Myeloma

    phase 1 small molecule completed

    1 trial

  7. ION269

    IONIS PHARMACEUTICALS INC

    Alzheimer Disease

    phase 1 small molecule terminated

    1 trial

  8. ION356

    IONIS PHARMACEUTICALS INC

    Pelizaeus-Merzbacher Disease

    phase 1 small molecule active

    1 trial

  9. ION464

    IONIS PHARMACEUTICALS INC

    Multiple System Atrophy

    phase 1 small molecule active

    1 trial

  10. ION537

    IONIS PHARMACEUTICALS INC

    Advanced Solid Tumors

    phase 1 small molecule completed

    1 trial

  11. ION547

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  12. ION904

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

  13. IONIS ANGPTL3-LRx

    IONIS PHARMACEUTICALS INC

    Hypertriglyceridemia

    phase 1 small molecule completed

    1 trial

  14. IONIS FXI-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Participants

    phase 1 small molecule completed

    1 trial

  15. IONIS MAPTRx

    IONIS PHARMACEUTICALS INC

    Mild Alzheimer's Disease

    phase 1 small molecule completed

    1 trial

  16. IONIS TMPRSS6-Lrx

    IONIS PHARMACEUTICALS INC

    Thalassemia

    phase 1 small molecule completed

    1 trial

  17. IONIS-APO(a)-LRx

    IONIS PHARMACEUTICALS INC

    Elevated Lipoprotein(a)

    phase 1 small molecule completed

    1 trial

  18. IONIS-ENaCRx

    IONIS PHARMACEUTICALS INC

    Healthy Subjects

    phase 1 small molecule completed

    1 trial

  19. ISIS 325568

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  20. ISIS 333611

    IONIS PHARMACEUTICALS INC

    Familial Amyotrophic Lateral Sclerosis

    phase 1 small molecule completed

    1 trial

  21. ISIS 353512

    IONIS PHARMACEUTICALS INC

    Inflammatory Diseases

    phase 1 small molecule completed

    1 trial

  22. ISIS 388626

    IONIS PHARMACEUTICALS INC

    Type 2 Diabetes Mellitus

    phase 1 small molecule completed

    1 trial

  23. ISIS 681257

    IONIS PHARMACEUTICALS INC

    Renal Impairment

    phase 1 small molecule completed

    1 trial

  24. Ionis AGT-LRx

    IONIS PHARMACEUTICALS INC

    Healthy Volunteers

    phase 1 small molecule completed

    1 trial

Frequently asked questions

What is the NovaPharmaNews pipeline directory?

It is a searchable index of 18,156 clinical development programs grouped by sponsor company, with phase (Phase 1–3), modality, trial status, and linked NCT IDs from ClinicalTrials.gov.

Where does pipeline data come from?

Program records are derived from ClinicalTrials.gov and linked to NovaPharmaNews company profiles. Trial status and phase reflect registry data at last sync — verify on ClinicalTrials.gov before investment or partnering decisions. See our data sources page for attribution.

How do I find pipeline programs by company or phase?

Use the search box to match program name, indication, company name, or slug. Results are ordered with late-stage (Phase 3) programs first. Open any row to view the full program profile under its sponsor company.

Data attribution and licensing: Data sources