Intelligence · Clinical Pipeline
R&D Pipeline Programs
ClinicalTrials.gov programs linked to pharma sponsors — phase, modality, and trial IDs for BD and competitive intelligence.
- Programs indexed
- 20,548
- Companies
- 1,769
- Drugs tracked
- 4,797
Quick answer
NovaPharmaNews tracks 20,548 pharmaceutical R&D pipeline programs sourced from ClinicalTrials.gov, linked to sponsor companies. Each profile includes development phase, modality, trial status, NCT identifiers, and indication text — searchable for business development and competitive intelligence.
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Sepiapterin
PTC THERAPEUTICS, INC.
Phenylketonuria
1 trial -
Shingrix powder and suspension for suspension for injection Herpes zoster vaccine (recombinant, adjuvanted), Cladribine Placebo, cladribine
Merck Sharp and Dohme
Generalized Myasthenia Gravis
1 trial -
Sildenafil placebo, Remidia, 20 mg, tabletki powlekane
Cardiol Therapeutics
Patients with functionally single ventricle (FSV - functionally single ventricle) after Fontan operation. The term "functionally single ventricle" refers to congenital heart defects in which one of the ventricles is not fully developed and/or one of the valves is atresia/hypoplastic as a result, it is not possible to correct the intracardiac defect. Then, there are indications for the Fontan operation, i.e. a palliative procedure - total cavo-pulmonary connection (TCPC). In patients with a functionally single ventricle, more than one operation is necessary to separate the systemic and pulmonary circulation. As a result of these procedures, Fontan circulation is created, which consists in bypassing the right heart chambers and directing the venous blood to the pulmonary artery. This leads to the removal of the right-to-left shunt and improvement of arterial blood saturation and reduction of volume overload of the systemic ventricle. At the same time, there is an increase in systemic venous pressure and a decrease in cardiac output. Low pulmonary resistance in these patients is crucial for maintaining optimal hemodynamic conditions both at rest and especially during exercise. Even a slight increase in pulmonary resistance leads to reduced pulmonary blood flow, reduced initial depression of a single ventricle, and consequently to reduced cardiac output and worsened exercise tolerance. Thus, pulmonary resistance in these patients should be not only normal, but also as low as possible to ensure adequate single ventricular filling and adequate cardiac output. There is evidence that patients with Fontan surgery increase pulmonary resistance over time. The increase in pulmonary resistance in these patients may result from several factors, and above all from the progressive dysfunction of a single systemic ventricle and the lack of a subpulmonary chamber ensuring pulsatile pulmonary flow. Although the Fontan operation in many patients with an univentricular heart is a very good method of palliative treatment, which undoubtedly extends the survival of children born with this heart defect, it also inevitably leads to severe complications developing over the years. Patients after the Fontan operation are also characterized by a significant reduction in exercise capacity, which is observed both in clinical practice in reference centres dealing with patients with congenital heart defects, and in multi-centre studies. Among other things, it was shown that children after the Fontan operation obtained 30% lower values of peak oxygen uptake in the ergospirometric test compared to the control group of healthy children (Amadero P et al., Heart 2018). The reduced exercise capacity of patients and the development of Fontan circulatory complications affect both the quality of life and the prognosis of adult patients with univentricular heart.
1 trial -
Simponi 50 mg solution for injection in pre-filled syringe., Simponi 45 mg/0.45 mL solution for injection in pre-filled pen., Simponi 100 mg solution for injection in pre-filled syringe.
Janssen-Cilag Pty Ltd
Ulcerative Colitis
1 trial -
Sodio Cloruro Fresenius Kabi Italia 0,9%, solvente per uso parenterale, Samyr placebo (saline solution), SAMYR 400 mg/5ml polvere e solvente per soluzione iniettabile
Mylan Pharma UK
Major Depression Disorders
1 trial -
Sodium chloride 0.372% solution, Dexamethasone sodium phosphate for encapsulation into autoerythrocytes
Quince Therapeutics
Ataxia Telangiectasia
1 trial -
Solcera, Preserved water
Alphapharm Pty Ltd
Actinic keratosis
1 trial -
Solifenacin succinate
Astellas Pharma Europe B. V.
Neurogenic Detrusor Overactivity
1 trial -
Solriamfetol
Ignis Therapeutics (Suzhou) Limited
Sleep Apnea, Obstructive
1 trial -
Solriamfetol 150 MG
Axsome Therapeutics
Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
1 trial -
Solriamfetol 150 mg
Axsome Therapeutics
Binge-Eating Disorder
1 trial -
Solriamfetol 150 mg
Axsome Therapeutics
Excessive Sleepiness
1 trial -
Solriamfetol 150 mg
Axsome Therapeutics
ADHD
1 trial -
Solriamfetol 300 mg
Axsome Therapeutics
Major Depressive Disorder
1 trial -
Solriamfetol 75mg, 150 mg, or 300 mg
Axsome Therapeutics
Binge-Eating Disorder
1 trial -
Solution for injection in pre-filled syringe without Ustekinumab 90, Solution for injection without Ustekinumab 45, STELARA 45 mg solution for injection, STELARA 90 mg solution for injection in pre-filled syringe, JNJ-77242113, Film-Coated Tablet without JNJ-77242113
Janssen-Cilag International N.V.
Moderate to Severe Plaque Psoriasis
1 trial -
Sonelokimab
MoonLake Immunotherapeutics
Hidradenitis Suppurativa
4 trials -
Sonelokimab
MoonLake Immunotherapeutics
psoriatic arthritis (PsA)
1 trial -
Sonelokimab
MoonLake Immunotherapeutics
Hidradenitis suppurativa (HS)
1 trial -
Sonelokimab
MoonLake Immunotherapeutics
Arthritis, Psoriatic
4 trials -
Sonelokimab, Placebo is a sterile solution in a single use prefilled syringe (PFS) intended for subcutaneous administration
MoonLake Immunotherapeutics
hidradenitis suppurativa (HS)
1 trial -
Sonelokimab, Placebo is a sterile solution in a single use prefilled syringe (PFS) intended for subcutaneous administration
MoonLake Immunotherapeutics
hidradenitis suppurativa (HS)
1 trial -
Sonelokimab, Placebo is a sterile solution in a single use prefilled syringe (pfs) intended for subcutaneous administration
MoonLake Immunotherapeutics
Psoriatic arthritis
1 trial -
Soquelitinib
Corvus Pharmaceuticals
Peripheral T-Cell Lymphoma, Not Otherwise Specified
1 trial
Frequently asked questions
What is the NovaPharmaNews pipeline directory?
It is a searchable index of 20,548 clinical development programs grouped by sponsor company, with phase (Phase 1–3), modality, trial status, and linked NCT IDs from ClinicalTrials.gov.
Where does pipeline data come from?
Program records are derived from ClinicalTrials.gov and linked to NovaPharmaNews company profiles. Trial status and phase reflect registry data at last sync — verify on ClinicalTrials.gov before investment or partnering decisions. See our data sources page for attribution.
How do I find pipeline programs by company or phase?
Use the search box to match program name, indication, company name, or slug. Results are ordered with late-stage (Phase 3) programs first. Open any row to view the full program profile under its sponsor company.
Data attribution and licensing: Data sources