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Patents

Browse 29,054 pharma-relevant US patents (A61K/A61P) linked to tracked companies. Patent cliff and LOE intelligence for BD teams.

29,054 patents indexed
patent

US 12331328

CRISPR/Cas9-mediated exon-skipping approach for USH2A-associated usher syndrome

Editas Medicine, Inc. Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12331334

Modified urokinase-type plasminogen activator polypeptides and methods of use

Vertex Pharmaceuticals Incorporated Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12331307

Modified immunization vectors

ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12331036

Heterocyclic RIP1 kinase inhibitors

Rigel Pharmaceuticals, Inc. Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12331057

Modulators of alpha-1 antitrypsin

Vertex Pharmaceuticals Incorporated Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12331079

Oncolytic virus platform to treat cancers with myxoma virus

ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12331126

OX40-binding polypeptides and uses thereof

Inhibrx Biosciences, Inc. Β· Granted Tue Jun 17 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 12 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325752

Immunoglobulin proteins that bind to NPR1 agonists

REGENERON PHARMACEUTICALS, INC. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325753

Method of using an anti-transferrin receptor antibody to deliver an oligonucleotide to a s

Dyne Therapeutics, Inc. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325750

Anti-Dectin-2 antibodies and methods of using

Bolt Biotherapeutics, Inc. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325715

Fluorous metal chelates compositions

The Regents of the University of California Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325711

3-(ethoxydifluoromethyl)-6-(5-fluoro-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)-[1,2,4]triazol

PRAXIS PRECISION MEDICINES, INC. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325732

Pro-insulin aspart structure and method for preparing insulin aspart

AMPHASTAR NANJING PHARMACEUTICALS INC Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325733

Binding domain

AUTOLUS LIMITED Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325691

Compounds and methods for treating cancer, neurological disorders, ethanol withdrawal, anx

The Board of Regents of the University of Texas System Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325699

Antibacterial compounds

BLACKSMITH MEDICINES, INC. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325708

Adenosine 2 receptor antagonists

Nektar Therapeutics Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325710

Substituted 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles for treating brain disorders

The Regents of the University of California Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325688

Gingerenone A prodrugs as sensotherapeutics and methods of use

The United States of America, as represented by the Secretary, Department of Health and Human Services Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325755

Macropinocytosing human anti-CD46 antibodies and targeted cancer therapeutics

The Regents of the University of California Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12326492

Systems and methods of detecting interstitial cystitis

LIPELLA PHARMACEUTICALS, INC. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12324843

Compositions and methods for delivery of biomacromolecule agents

THE REGENTS OF THE UNIVERSITY OF MICHIGAN Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12325854

Crispr-CPF1-related methods, compositions and components for cancer immunotherapy

Editas Medicine, Inc. Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12324798

Leonurine nanocomposite hydrogel and preparation methods and applications thereof

WEST CHINA HOSPITAL, SICHUAN UNIVERSITY Β· Granted Tue Jun 10 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 05 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted