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Patents

Browse 63 pharma-relevant patents (US and EP, A61K/A61P) linked to tracked companies. Patent cliff and LOE intelligence for BD teams.

29,054 patents indexed
patent

US 11225469

Inhibitors of phosphoglycerate dehydrogenase (PHGDH) and uses thereof

The United States of America, as represented by the Secretary, Department of Health and Human Services Β· Granted Tue Jan 18 2022 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 13 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10961200

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

The United States of America, as represented by the Secretary, Department of Health and Human Services Β· Granted Tue Mar 30 2021 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Mar 25 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10954228

1 H-pyrazol-1-yl-thiazoles as inhibitors of lactate dehydrogenase and methods of use there

NATIONAL INSTITUTES OF HEALTH, UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES Β· Granted Tue Mar 23 2021 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Mar 18 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10869871

Compositions and methods of modulating short-chain dehydrogenase activity

The Board of Regents of the University of Texas System Β· Granted Tue Dec 22 2020 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Dec 17 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10752626

Iso-citrate dehydrogenase (IDH) inhibitor

SHANGHAI METON PHARMACEUTICAL CO., LTD Β· Granted Tue Aug 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10738047

Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulat

The United States of America, as represented by the Secretary, Department of Health Β· Granted Tue Aug 11 2020 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 06 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10351532

Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

The United States of America, as represented by the Secretary, Department of Health and Human Services Β· Granted Tue Jul 16 2019 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 11 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10335382

Use of hydrogen sulfide synthesis inhibitors for cancer therapy

The Board of Regents of the University of Texas System Β· Granted Tue Jul 02 2019 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 27 2039 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 10131659

Iodonium analogs as inhibitors of NADPH oxidases and other flavin dehydrogenases; formulat

The United States of America, as represented by the Secretary, Department of Health and Human Services Β· Granted Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Nov 15 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9969719

Substituted 2-hydrogen-pyrazole derivative serving as anticancer drug

Medshine Discovery Inc. Β· Granted Tue May 15 2018 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon May 10 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9889081

Aldehyde dehydrogenase inhibitors as novel depigmenting agents

The Board of Regents of the University of Texas System Β· Granted Tue Feb 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Feb 08 2038 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9801863

Inhibitors of short-chain dehydrogenase activity for modulating hematopoietic stem cells a

The Board of Regents of the University of Texas System Β· Granted Tue Oct 31 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Oct 26 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9789116

Compositions and methods of modulating short-chain dehydrogenase activity

The Board of Regents of the University of Texas System Β· Granted Tue Oct 17 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Oct 12 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9765055

Intramolecular hydrogen-bonded nitric oxide synthase inhibitors

Northwestern University Β· Granted Tue Sep 19 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 14 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9713459

Method and system for in vivo hydrogen peroxide detection with ultrasound

The Regents of the University of California Β· Granted Tue Jul 25 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 20 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9616076

Methods for treating viral infections using hydrogen sulfide donors

The Board of Regents of the University of Texas System Β· Granted Tue Apr 11 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Apr 06 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9605026

Hydrogen-bond surrogate peptides and peptidomimetics for p53 reactivation

THE REGENTS OF THE UNIVERSITY OF MICHIGAN Β· Granted Tue Mar 28 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Mar 23 2037 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9534007

Methods and compositions for treatment of cyanide and hydrogen sulfide toxicity

United States of America as represented by the Secretary of the Air Force Β· Granted Tue Jan 03 2017 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Dec 29 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9504701

Methods for treating viral infections using hydrogen sulfide donors

The Board of Regents of the University of Texas System Β· Granted Tue Nov 29 2016 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Nov 24 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9399666

Inhibiting interaction between the HIF-1ALPHA and p300/CBP with hydrogen bond surrogate-ba

Arizona Board of Regents on Behalf of the University of Arizona Β· Granted Tue Jul 26 2016 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 21 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9333264

Biocompatible polymeric nanoparticles degrade and release cargo in response to biologicall

The Regents of the University of California Β· Granted Tue May 10 2016 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon May 05 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9238653

Antimalarial agents that are inhibitors of dihydroorotate dehydrogenase

The Board of Regents of the University of Texas System Β· Granted Tue Jan 19 2016 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 14 2036 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9216983

Dihydroorotate dehydrogenase inhibitors with selective anti-malarial activity

The Board of Regents of the University of Texas System Β· Granted Tue Dec 22 2015 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Dec 17 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 9018216

Solid forms of (R)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1H-benzo[d]im

Vertex Pharmaceuticals Incorporated Β· Granted Tue Apr 28 2015 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Apr 23 2035 00:00:00 GMT+0000 (Coordinated Universal Time)

granted