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Patents

Browse 29,054 pharma-relevant US patents (A61K/A61P) linked to tracked companies. Patent cliff and LOE intelligence for BD teams.

29,054 patents indexed
patent

US 12377112

Methods of treating neurocognitive disorders, chronic pain and reducing inflammation

Compass Pathfinder Limited Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378553

Modified double-stranded RNA agents

Alnylam Pharmaceuticals, Inc. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378557

Treatment of sepsis with PCSK9 and LDLR modulators

REGENERON PHARMACEUTICALS, INC. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378540

Fusion proteins comprising acid alpha-glucosidase enzymes and methods thereof

DENALI THERAPEUTICS INC. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378337

Lipid nanodiscs solubilized through poly(acrylic acid-co-styrene) copolymers

The Regents of the University of California Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378558

RNAi agents for inhibiting expression of complement factor B (CFB), pharmaceutical composi

Arrowhead Pharmaceuticals, Inc. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378280

Deoxynucleic guanidines (DNG)-modified oligonucleotides and methods of synthesizing deoxyn

Northwestern University Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378286

Methods and compositions useful for inhibiting growth of certain bacteria

The Regents of the University of California Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378288

Multimeric bicyclic peptide ligands

BicycleTx Limited Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378560

Sequence multiplicity within spherical nucleic acids

Northwestern University Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378245

Crystalline forms of an RSK inhibitor

PHOENIX MOLECULAR DESIGNS Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378248

A1 adenosine receptor agonists and methods of use thereof

The United States of America, as represented by the Secretary, Department of Health and Human Services Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378256

Heterocyclic compound

Takeda Pharmaceutical Company Limited Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12379385

Methods of treating patients afflicted with irritable bowel syndrome, inflammatory bowel d

Maximus Diagnostic Technologies LLC Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378258

Biologically active molecules, conjugates thereof, and therapeutic uses

REGENERON PHARMACEUTICALS, INC. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378199

Rigidified pentadentate chelating agents useful for the [Al18F]2+ labelling of biomolecule

UNIVERSITΓ€ DEGLI STUDI DEL PIEMONTE ORIENTALE β€œA. AVOGADRO” Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378193

Anti-arrhythmicity agents

The Regents of the University of California Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378231

Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof

APOGEE PHARMACEUTICALS, INC. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378241

Pyridine derivative as FGFR and VEGFR dual inhibitors

CGeneTech (Suzhou, China) CO., Ltd. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12378195

Aminated psilocybin derivatives and methods of using

Enveric Biosciences Canada Inc. Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12377252

Implantation devices, system, and methods

Vertex Pharmaceuticals Incorporated Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12377191

Chondroinductive peptides and compositions and methods of use thereof

The Board of Regents of the University of Oklahoma Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12377186

Antimicrobial biopolymer compositions, methods of synthesis, and applications of use

Arizona Board of Regents on Behalf of the University of Arizona Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12377135

GHRH antagonists for use in a method of treating sarcoidosis

United States Government as represented by the Department of Veterans Affairs Β· Granted Tue Aug 05 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 31 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted