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Patents

Browse 912 pharma-relevant patents (US and EP, A61K/A61P) linked to tracked companies. Patent cliff and LOE intelligence for BD teams.

29,054 patents indexed
patent

US 12428455

Dominant negative CEBPB and CEBPD proteins and methods of use for decreasing viability of

The Regents of the University of California Β· Granted Tue Sep 30 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 25 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12427170

Universal donor cells

CRISPR THERAPEUTICS AG Β· Granted Tue Sep 30 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 25 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12419955

Method for efficiently infecting human natural killer cells and other immune cells with ps

Beijing Gene MINK Biotechnology CO.LTD Β· Granted Tue Sep 23 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12421517

Genetic modification of mammalian cells to confer resistance to CSF1R antagonists

The Regents of the University of California Β· Granted Tue Sep 23 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12421316

Bispecific immunotoxins targeting human CD25+CCR4+ tumors and regulatory T-cells

The Regents of the University of Colorado, a Body Corporate Β· Granted Tue Sep 23 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12421302

CAR-t cells and autoimmune diseases

The Regents of the University of California Β· Granted Tue Sep 23 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 18 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12414968

Compositions comprising bacterially derived minicells and methods of using the same

EnGeneIC Molecular Delivery Pty Ltd Β· Granted Tue Sep 16 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 11 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12398373

Enhanced immune effector cells and use thereof

Fate Therapeutics, Inc. Β· Granted Tue Aug 26 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 21 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12391923

SIRPΞ±-silenced natural killer (NK) cells

The Regents of the University of California Β· Granted Tue Aug 19 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 14 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12391739

Method for producing gamma delta T cells

Takeda Pharmaceutical Company Limited Β· Granted Tue Aug 19 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 14 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12385013

Differentiation of pancreatic endocrine cells

Vertex Pharmaceuticals Incorporated Β· Granted Tue Aug 12 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12383629

DNA-affibody-drug nanoparticles for inhibiting the metastasis of cancer cells overexpressi

ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY Β· Granted Tue Aug 12 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Aug 07 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12370256

Activation of resident memory T cells for the treatment of cancer

Regents of the University of Minnesota Β· Granted Tue Jul 29 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12371665

Differentiation of pancreatic endocrine cells

Vertex Pharmaceuticals Incorporated Β· Granted Tue Jul 29 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 24 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12365875

Methods for generating skeletal muscle progenitor cells

The Regents of the University of California Β· Granted Tue Jul 22 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12365873

Methods for transducing immune cells

Allogene Therapeutics, Inc. Β· Granted Tue Jul 22 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 17 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12358968

Utilization of CD39 and CD103 for identification of human tumor reactive T cells for treat

Providence Health & Servicesβ€”Oregon Β· Granted Tue Jul 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 10 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12351824

Method for producing natural killer cells from pluripotent stem cells

Takeda Pharmaceutical Company Limited Β· Granted Tue Jul 08 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 03 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12344655

Gene-edited natural killer cells

CRISPR THERAPEUTICS AG Β· Granted Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12344656

Genetically engineered T cells having improved persistence in culture

CRISPR THERAPEUTICS AG Β· Granted Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12343448

Use of stem cells produced by stem cell generator in treatment of hematopoietic damage

East China University of Science and Technology Β· Granted Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12343397

Drug-resistant immune cells and methods of use thereof

Regents of the University of Minnesota Β· Granted Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12338459

DNA-chimeric antigen receptor T cells for immunotherapy

ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY Β· Granted Tue Jun 24 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 19 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted patent

US 12319740

Methods for production of tissue resident memory-like T cells and use thereof

The Board of Regents of the University of Texas System Β· Granted Tue Jun 03 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon May 29 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted