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Patents

Browse 65 pharma-relevant US patents (A61K/A61P) linked to tracked companies. Patent cliff and LOE intelligence for BD teams.

29,054 patents indexed
patent

US 12427170

Universal donor cells

CRISPR THERAPEUTICS AG Β· Granted Tue Sep 30 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Sep 25 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12344656

Genetically engineered T cells having improved persistence in culture

CRISPR THERAPEUTICS AG Β· Granted Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12344655

Gene-edited natural killer cells

CRISPR THERAPEUTICS AG Β· Granted Tue Jul 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 26 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12304968

T-cells expressing anti-LIV1 chimeric antigen receptor

CRISPR THERAPEUTICS AG Β· Granted Tue May 20 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon May 15 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12263227

Optimized mRNA encoding CAS9 for use in LNPs

CRISPR THERAPEUTICS AG Β· Granted Tue Apr 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Mar 27 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12247201

Materials and methods for treatment of autosomal dominant retinitis pigmentosa

CRISPR THERAPEUTICS AG Β· Granted Tue Mar 11 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Mar 06 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12241087

Compositions and methods for differentiating stem cells into NK cells

CRISPR THERAPEUTICS AG Β· Granted Tue Mar 04 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Feb 27 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12227763

Methods and compositions for treating cancer

CRISPR THERAPEUTICS AG Β· Granted Tue Feb 18 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Feb 13 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12215316

Materials and methods for treatment of usher syndrome type 2A

CRISPR THERAPEUTICS AG Β· Granted Tue Feb 04 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 30 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12215320

Compositions and methods for gene editing by targeting transferrin

CRISPR THERAPEUTICS AG Β· Granted Tue Feb 04 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 30 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12188060

Messenger RNA encoding Cas9 for use in genome-editing systems

CRISPR THERAPEUTICS AG Β· Granted Tue Jan 07 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 02 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12186406

Materials and methods for treatment of hereditary haemochromatosis

CRISPR THERAPEUTICS AG Β· Granted Tue Jan 07 2025 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 02 2045 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12122998

Materials and methods for treatment of usher syndrome type 2A and/or non-syndromic autosom

CRISPR THERAPEUTICS AG Β· Granted Tue Oct 22 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Oct 17 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12037616

Methods and compositions for treating angiopoietin-like 3 (ANGPTL3) related conditions

CRISPR THERAPEUTICS AG Β· Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 12016932

Gene editing for hemophilia A with improved factor VIII expression

CRISPR THERAPEUTICS AG Β· Granted Tue Jun 25 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 20 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11958908

Compositions and methods for the depletion of CD117+ cells

CRISPR THERAPEUTICS AG Β· Granted Tue Apr 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Apr 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11926676

Masked chimeric antigen receptor specific to tyrosine-protein kinase like 7 (PTK7) and imm

CRISPR THERAPEUTICS AG Β· Granted Tue Mar 12 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Mar 07 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11866727

Materials and methods for treatment of glycogen storage disease type 1A

CRISPR THERAPEUTICS AG Β· Granted Tue Jan 09 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jan 04 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11857574

Genetically engineered T cells with Regnase-1 and/or TGFBRII disruption have improved func

CRISPR THERAPEUTICS AG Β· Granted Tue Jan 02 2024 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Dec 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11851653

Materials and methods for treatment of alpha-1 antitrypsin deficiency

CRISPR THERAPEUTICS AG Β· Granted Tue Dec 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Dec 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11833225

Methods and compositions for efficient gene deletion

CRISPR THERAPEUTICS AG Β· Granted Tue Dec 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Nov 30 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11827877

Compositions and methods for genomic editing by insertion of donor polynucleotides

CRISPR THERAPEUTICS AG Β· Granted Tue Nov 28 2023 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Nov 23 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11679131

Genetically engineered T cells with regnase-1 and/or TGFBRII disruption have improved func

CRISPR THERAPEUTICS AG Β· Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

granted
patent

US 11679130

Genetically engineered t cells with Regnase-1 and/or TGFBRII disruption have improved func

CRISPR THERAPEUTICS AG Β· Granted Tue Jun 20 2023 00:00:00 GMT+0000 (Coordinated Universal Time) Β· Expires Mon Jun 15 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

granted