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EUROPE · EMA INTELLIGENCE
EU edition · 2025-10
EU pharma briefing — 2025-10
 
Harmonized Standards for Medical Devices Adopted

REGULATORY · EMA

Harmonized Standards for Medical Devices Adopted

The European Commission issued Implementing Decision (EU) 2025/2078 on 17 October 2025, adopting four harmonized standards for surgical clothing, drapes, medical face masks, and sterilizers under the MDR.

 
MO

REGULATORY · EMA

Monitoring of Medicine Shortages Under New Pharma Package

The new EU Pharma Package mandates systematic monitoring of anticipated and actual medicine shortages by EMA and national authorities, based on notifications from industry stakeholders.

 
GO

REGULATORY · MHRA

Guidance on Clinical Investigations of Medical Devices

The MHRA has released guidance for manufacturers regarding clinical investigations of medical devices, effective October 2025.

 
New EU Implementing Regulation on Medical Technologies

ARTICLE

New EU Implementing Regulation on Medical Technologies

On 17 October 2025, the European Commission adopted Implementing Regulation (EU) 2025/2086, establishing procedural rules and templates for medical technology evaluations under HTA Regulation (EU) 2021/2282. This regulation introduces International Reliance Routes...

 
Capability Confirmation for EU States

NEWS

Capability Confirmation for EU States

FDA confirmed the capability of nine EU states for human and veterinary GMP inspections, including Sweden, Latvia, and Germany, between June 2023 and September 2025.

 
EU

NEWS

EU-USA MRA Batch Testing Waiver

The EU-USA Mutual Recognition Agreement allows for a batch testing waiver for human medicines, operational since July 2019, while the veterinary waiver is pending full EU state recognitions.

 
AU

NEWS

Assessments Under EU-USA MRA

As of October 2025, assessments are ongoing for Malta and Croatia under the EU-USA MRA for veterinary product manufacturer inspections.

 

Key Statistics

9
EU States Confirmed for GMP Inspections
4
New Standards Adopted Under MDR
MHRA Actions Against Businesses
Year-to-date
 

Notable Resources

GUIDANCE · MHRA
Latest guidance for manufacturers on conducting clinical investigations of medical devices.
BLOG · Parexel
Analysis of strategic implications for drug developers under the new EU Pharma Package.
 

Official sources

  1. https://www.ema.europa.eu/en/documents/other/qa-impact-eu-usa-mutual-recognition-agreement-marketing-authorisation-applications-relevant-variations-revised-1st-october-2025_en.pdf
  2. https://www.ema.europa.eu/en/documents/other/questions-answers-impact-mutual-recognition-agreement-mra-between-european-union-united-states-1st-october-2025_en.pdf
  3. https://assets.publishing.service.gov.uk/media/68e3b0abef1c2f72bc1e4e17/Guidance_for_mfrs_on_clinical_investigations-October_2025.pdf
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