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AMERICAS · FDA INTELLIGENCE
US edition · 2026-01
US pharma briefing — 2026-01
 
Increase in Drug Quality Inspections

NEWS

Increase in Drug Quality Inspections

The FDA conducted 972 drug quality inspections in 2024, marking a 27% increase from the previous year, with a significant focus on foreign manufacturing sites.

 
WL

NEWS

Warning Letters Highlight cGMP Violations

Approximately 35% of FY2025 warning letters cited cGMP violations, with a notable emphasis on contract manufacturers and CMOs, indicating a tightening of oversight.

 
EO

NEWS

Expansion of the 'Green List' Mechanism

The FDA's 'Green List' now targets GLP-1 products, with potential expansion to other high-risk classes, reflecting heightened scrutiny on foreign API sources.

 
FDA Enforcement Trends: January 2026 Overview

ARTICLE

FDA Enforcement Trends: January 2026 Overview

In January 2026, the FDA continued its rigorous enforcement of drug quality standards, with a focus on foreign manufacturing sites. The agency conducted inspections revealing significant compliance issues, particularly in contract manufacturing...

 
New EU Regulations on Drug Approval Processes

REGULATORY · EMA

New EU Regulations on Drug Approval Processes

The European Medicines Agency has implemented new regulations aimed at streamlining drug approval processes, focusing on enhancing patient safety and expediting access to innovative therapies.

 
SG

REGULATORY · EMA

Strengthened Guidelines on Pharmacovigilance

Revised pharmacovigilance guidelines emphasize the importance of post-market surveillance and risk management plans, ensuring ongoing safety monitoring of medicinal products.

 
IT

REGULATORY · EMA

Increased Transparency in Clinical Trials

New transparency measures require detailed reporting of clinical trial results, aiming to improve public access to information and enhance trust in the pharmaceutical sector.

 

Numbers of the month

Drug Quality Inspections Conducted
+27% YoY
New Import Alerts Issued
Sharp increase from previous years
cGMP Violations in Warning Letters
Notable focus on contract manufacturers
 

Reports & resources

REPORT · Intuition Labs
An in-depth analysis of FDA enforcement actions and trends affecting the pharmaceutical industry in 2026.
GUIDANCE · DRK Research
Guidance on best practices for maintaining compliance with current Good Manufacturing Practices in the pharmaceutical sector.
REPORT · GMP Compliance
Insights into recent FDA warning letters and the common deficiencies cited in the pharmaceutical industry.
 

Official sources

  1. https://www.fda.gov/media/191472/download?attachment
  2. https://www.fda.gov/media/191365/download
  3. https://www.federalregister.gov/documents/2026/02/20/2026-03326/agency-information-collection-activities-proposed-collection-comment-request-current-good
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US · Edition 2026-01 · B2B pharma intelligence, generated and reviewed by editors.
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